Putting the “good” into Good Clinical Practice

Good Clinical Practice

Clinical research is like a foundation stone upon which a tower of evidence is erected which helps in the better understanding of the cause of the disease, improvement in the diagnosis treatment and mechanism of human biology (Trauter,1997). It is only the systematically carried out research which has made possible the increase in the life expectancy and decrease in human sufferings. While carr...

Good Clinical Practice Training

Good Clinical Practice (GCP) is an international standard for the design, conduct, performance, monitoring, auditing, recording, analyses, and reporting of clinical trials. The goal of GCP is to ensure the protection of the rights, integrity, and confidentiality of clinical trial participants and to ensure the credibility and accuracy of data and reported results. In the United States, trial sp...

Good Scientific Practice (gsp) and Good Clinical Practice (gcp)

The Responsibility of the Institutional Review Board in Good Clinical Practice: First, Do No Harm

Dear Editor,I read with interest the article on outpatient management of burn wounds published in a recent issue of the IJMS.1 There are many questions that arise which are worth mentioning. Under the methodology section, no description was provided on how patients were randomized into the two treatment arms and, therefore, it is not possible to assess how confounding variables were controlled....

Translating evidence into practice: how good is good enough?

The birth of the evidence-based medicine (EBM) movement in the early 1990s generated a greater interest in measuring the extent to which scientific knowledge was appropriately applied to therapeutic decisions. Investigators sought to challenge the widespread belief that only a minority of treatments provided to patients were based upon the best available scientific evidence. In 1995 Ellis and c...